What’s the difference?

Synonyms are always the big obstacle for the non-native speakers, and therefore, concordancer can help us distinguish the way of synonyms' usage.
1. Large (adj)
Usually link with quantity
Ex: a large amount of output…
a large groups of students…
a large numbers of textbooks…
a large proportions of a group of teacher…
a large scale project…

2. Big (adj)
Often come with more concrete substance or numbers
Ex: The big three should…
Life in the big house…
The big man in his own town…

All the examples are From NTNU web Concordaners